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Research indicates that genetically engineered Lactobacillus gasseri strains exhibiting high expression of specific genes demonstrate more pronounced anti-inflammatory effects in DSS-induced IBD mouse models compared to wild-type strains, suggesting that modifying antioxidant enzymes in probiotics may enhance their anti-inflammatory activity (194)

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Biochemistry 40:168893, PMID: 11327828 Marshall HE, Hess DT, Stamler JS (2004) S -nitrosylation: physiological regulation of NF-kappaB

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