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Semaglutide may increase your energy expenditure by stimulating the GLP-1 receptors in the brain, which are involved in regulating motor activity and reward pathways
However, some people did not reach their individual treatment goals with this dose in the STEP 1 trial in people with overw*ight or ob*sity
Patients starting semaglutide are often already on metformin or proton pump inhibitors (which block tablet absorption)
GLP-1 medications like Mounjaro (tirzepatide) and Wegovy (semaglutide) reduce hunger and cravings, helping us lose weight by eating fewer calories
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