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[4] The liver stores approximately two to five years' worth of B12, which means deficiency may not become clinically apparent until well after surgery

The spot for the needle may be marked with a pen to help another professional find the best site

There was also no long-term follow-up to assess if any delayed complications (for example, abnormal tissue growth or tumor formation) occurred after the injection

For instance, one study notes that people with excess weight or obesity appear to have lower vitamin B12 levels than people who have a body mass index (BMI) in the normal range ( Additional research has observed that people who voluntarily took vitamin B12 supplements gained between 2.517 fewer pounds (1.27.7 kg) over 10 years than those who did not supplement with this vitamin ( Still, such observational studies cannot confirm whether low vitamin B12 levels are what caused the weight gain, nor whether theyre what protected against low levels

Patients can usually return to their regular activities immediately afterward