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These peptides represent a novel class of therapeutic agents that may offer alternatives to traditional treatment approaches for various pathological conditions

These findings suggest that oxidative stress has an important role in controlling the A level in neurons differentiated from DS patient-derived iPSCs and that N-acetylcysteine can be a potential therapeutic option to ameliorate the A secretion

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Ruvolo PP, R-Y W, Ruvolo VR, Jacamo R, McQueen T, Borthakur G, Qiu YH, Kevin R Coombes KR, Zhang N, Shpall EJ, Champlin RE, Garzon R, Marcucci G, Croce CM, Konopleva M, Andreeff M , Kornblau SM