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Often associated with poor outcomes, acute crises were not observed for a five-year follow-up period following thiamin supplementation (300-400 mg/day) early diagnosis and immediate treatment with biotin and thiamin led to positive outcomes (118)
252 For example, Zhan et al
ROS-triggered endothelial cell death mechanisms: focus on pyroptosis, parthanatos, and ferroptosis
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Perinatal brain injury: mechanisms, prevention, and outcomes
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