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doi: 10.1089/jir.1990.10.403 107
Contexto regulatorio : Cosmtica : aprobado como ingrediente cosmtico en USA (FDA OTC monograph), Unin Europea (CosIng), Japn, Corea, Australia, Mxico (COFEPRIS) y la mayora de jurisdicciones
335,336 First reported as the first reversible METAP inhibitor (METAPi) in 2003, LAF389 is a natural benzimide compound with dual METAP 1i and METAP 2i activities
both remain in clinical development, and their specific combination does not exist as a registered investigational product
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