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High cortisol levels can lead to depletion of glutathione, a critical antioxidant involved in the detoxification of harmful substances

It also acts as a vital cofactor for the antioxidant enzyme glutathione peroxidase (GPx) 20

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Benefits of LixiLan, a titratable fixed-ratio combination of insulin glargine plus lixisenatide, versus insulin glargine and lixisenatide monocomponents in type 2 diabetes inadequately controlled on oral agents: The LixiLan-O randomized trial

[5] [16] This multi-receptor activity drives significant reductions in appetite, caloric intake, and body weight effects that, while therapeutically promising, can also influence how the body regulates temperature