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In line with this notion, pharmacologic or genetic suppression of GLP-1R in the lateral septum attenuates the ability of cocaine to activate the mesolimbic dopamine system, as assessed by hyperactivity, reward in the CPP test, and dopamine enhancement in the NAc (Reddy et al., 2016)

Szklarczyk D, Gable AL, Lyon D, Junge A, Wyder S, Huerta-Cepas J, Simonovic M, Doncheva NT, Morris JH, Bork P, et al

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Oral administration is more convenient for daily dosing and avoids additional injection sites beyond the weekly tirzepatide shot

Through their utilization management programs, PBMs can influence prescribers behavior and medication use, directly impacting health outcomes