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The iPLA 2 family is composed of nine enzymes and is also referred to as the patatin-like phospholipase domain-containing lipase (PNPLA) family
The glutamate residue is linked through its side-chain carboxyl, giving a gamma-glutamyl bond rather than a standard alpha-peptide bond, which is why the molecule resists most intracellular peptidases and is cleaved chiefly by gamma-glutamyl transpeptidase at the cell surface
10.1038/227680a0 25 LagmanM.LyJ.SaingT.SinghM
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The liver doesnt store and release excessive amounts of glucose when blood glucose levels are in a healthy range
Patients sometimes ask whether a 5th injection would extend the benefit
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