Future optimization strategies include the development of brain-targeted prodrugs (e.g., ester modifications, peptide conjugation), the design of nanodelivery systems (PLGA, liposomes, exosome encapsulation) to enhance brain accumulation, and the identification of next-generation RTA molecules (such as SRS1192 and SRS16-86) with improved bloodbrain barrier permeability and metabolic stability
In particular, vitamin E, after acting as an antioxidant by reducing lipid radicals, is restored to its reduced form by vitamin C
The researchers also found that the benefits of GLP-1 therapy were especially pronounced in older adults, women, and certain racial subgroups
Take two capsules twice daily with water, giving a total of four capsules across the day
Additionally, staying hydrated and consuming an adequate amount of fiber can aid in digestion and enhance the absorption of L-Carnitine