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At the cellular level, under hypoxic conditions, the hypoxiainducible factor (HIF)prolyl hydroxylase family of enzymes (PHD13) lose their ability to hydroxylate HIF because they rely on O 2 for their enzymatic activity [139]
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One caveat worth internalizing: marketing claims in this category outpace the clinical evidence
Conclusion The effects of GLP-1 RAs on HF surrogate endpoints vary in HF patients across the LVEF spectrum
As a GLP-1 receptor agonist, Ozempic is frequently used to help people with type 2 diabetes control their blood sugar levels
ISBN 978-0-253-10925-5
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