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NNMT plays a key role in regulating energy metabolism and fat storage

Additionally, the NNMT substrate nicotinamide 12 is metabolized by the microbiome 56,57 , and thus NNMTi may modulate substrate availability, potentially influencing microbial metabolic capacity to drive the NNMTi-mediated weight loss

Metabolism and Weight Management Amino acids play a role in fat metabolism, insulin sensitivity and appetite regulation

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