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The supernatant was used for the analysis of LPO (Reference Ledwozyw, Michalak and Stepie25) , nitric oxide (NO) (Reference Miranda, Espey and Wink26) , GSH (Reference Beutler27) , glutathione-S-transferase (GST) (Reference Habig and Jakoby28) , SOD (Reference Mylroie, Collins and Umbles29) and tissue factor (TF) (Reference Ingram30) activities

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EAE experiments were terminated at the following stages of disease development: the onset stage is defined as the first time point at which immunized animals lose weight (710%) compared to the previous day, peak disease is defined as the first day the animals display a clinical score of 34 (with peak in scores), and recovery is defined as a distinct drop in score from a previous peak score of 34 to 12

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