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Tirzepatide-treated patients demonstrated significantly greater improvements than comparators for most of the measured PROs at primary timepoint in all five studies

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has served as a consultant or speaker within the past 12 months for Eli Lilly and Structure Therapeutics

The approval does not restrict tirzepatide to any particular line of therapy, meaning it can be used as monotherapy or in combination with other antidiabetic medications, including metformin, sulfonylureas, sodium-glucose cotransporter-2 (SGLT2) inhibitors, and insulin

Anxiety on tirzepatide is documented in some patients