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The focus on these specific strategies in research and therapeutic development highlights their potential to significantly enhance efficacy and outcomes

However, it's essential to approach supplementation with caution, ensuring you follow recommended doses and consult with a healthcare professional if needed

Notably, excess hemin exposure exacerbates the disease severity of SCD 19,20 and heme-scavenging strategies such as intravenous infusion of hemopexin are propective 21,22

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J Periodontal Res 38(5):502507