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A simple way to avoid the issue is to take creatine with food, avoid loading phases, or take multiple smaller doses (3-5 grams) during a loading phase

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Glutamine does appear to increase weight loss, although studies show muscle and fat were lost in equal measure, making it a less-than-ideal diet supplement Its worth noting that Glutamine is used as a supplement in medical conditions that lead to glutamine deficiency such as Cancer and HIV