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At the end of treatment, the cell culture supernatants of each group were collected
At 26 weeks, changes in apoC-III, rather than body weight, were the most accurate predictors of changes in triglyceride levels with tirzepatide, accounting for up to 22.9% of the variability observed.Treatment with tirzepatide demonstrated a dose-dependent decrease in apoC-III and apoB levels, as well as a reduction in the number of large TRLP and small LDLP
These drugs have shown efficacy beyond glycaemic regulation, including significant weight loss, cardiovascular protection, and possible advantages for renal function
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