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In the context of GLP-1RAs, metabolic reprogramming involves modulating energy metabolism and regulating cardiac function and pathological remodeling through various mechanisms (12, 13)
Posteriormente, el cuerpo puede reducir o regenerar otra molcula de glutatin y as recuperar los niveles del mismo
Previously, the GLP-1R agonist liraglutide has been shown to attenuate EMT changes in the UUO model by inhibiting TGF-1/Smad3 and ERK1/2 signaling pathways ( The present study in kidney transplantation model also indicates that TB001 significantly enhances lipid metabolism (marked by increased CPT1A expression in TECs) and reduces PKC- and PKC- expression, thereby attenuating kidney allograft fibrosis
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Wang H, Chen S, Tang Y, Nie K, Gao Y, Wang Z, et al
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