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Compounding gastrointestinal side effects (severe nausea, vomiting, dehydration), increased hypoglycemia risk, unpredictable drug-drug interactions, and complete absence of safety data

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This in turn lowers blood sugar by signalling cells to take up glucose (sugar)

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The process involves two distinct but sequential stages: regulatory approval by the MHRA, followed by health technology assessment (HTA) by the National Institute for Health and Care Excellence (NICE)