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Epitalon has been shown to significantly increase the expression of key antioxidant enzymes: Superoxide dismutase (SOD-1) Catalase NAD(P)H quinone dehydrogenase 1 (NQO1) These effects are mediated via the Keap1/Nrf2 signaling pathway [40, 41]: a master regulator of cellular redox balance

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Cytosolic NAD + is synthesized by NMNAT2 localized in the cytoplasm and Golgi, where it is essential for glycolysis 82

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Delays in Referral and Enrolment Are Associated with Mitigated Benefits of Cardiac Rehabilitation after Coronary Artery Bypass Surgery