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Thorne, a supplement company selling the product, told WIRED that its berberine sales have increased more than 165 percent in the second quarter of 2023 so far, compared to sales in the same time period last year

However, it is important to note that humans have fewer C-cells and GLP-1 receptors in the thyroid gland compared to rodents, and no C-cell changes have been observed in clinical trials involving patients treated with GLP-1 RAs [26]

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