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Pathological hypertrophy, in contrast, is commonly linked to hypertension, valvular disease, diabetes, obesity, cardiomyopathy, renal disease, or aging and may progress to fibrosis, capillary rarefaction, diastolic dysfunction, systolic failure, arrhythmia, and sudden death ( The adult heart has high ATP demand and normally oxidizes multiple substrates, especially fatty acids, glucose, lactate, ketone bodies, and amino acids
L-Carnitine helps transport fatty acids into cells, where they are burned for energy, leading to increased fat oxidation
Therefore, future research efforts will be necessary to clarify the mechanism of enzyme inhibition played by auranofin on GSTs
5 These lesions appear as brown, flat plaques with an irregular surface
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