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blank ) / slope Kinetic method: Total glutathione = (Slope c) sample Slope c) blank ) / slope b) a) Since the values obtained by these equations are the amount of total glutathione in treated sample solutions, further calculations are necessary if the actual concentrations of glutathione in cells or tissues need to be determined

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VPA can also reduce HDAC activity by inducing the proteosome-dependent degradation of HDAC2 in cultured cells [81]