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Statistical analysis A paired t-test was used to compare changes from baseline to endpoint (Week 24)
Both should stay in carry-on bags and in their original containers for easy identification
That makes it a strong option for laboratories focused on pathway mapping, structured signaling models, and metabolic system analysis with a narrower research lens
Given a 95% confidence level (Z = 1.96) and a 5% margin of error (E = 0.05), and assuming a proportion (P) of 0.5 to maximize the required sample size, we calculated the necessary sample size using RaSoft sample size calculator (Raosoft, Inc., Seattle, WA, USA) [24] to be approximately 384
Ongoing monitoring typically involves monthly or quarterly check-ins during dose titration, regular assessment of weight loss progress and tolerability, periodic lab work to monitor metabolic parameters, and screening for potential complications
