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Deficiency is increasingly recognized as a risk factor in coronary artery disease, asthma, neurodegenerative disorders, cognitive-behavioral problems, and various types of cancer

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The UL was established for generally healthy people, and the FNB noted that individuals with liver or kidney disease, Parkinson's disease, depression, or inherited trimethylaminuria might be at increased risk of adverse effects when consuming choline at levels near the UL (32)

Diagnosis was based on clinical, radiological, endoscopy and histological findings