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b , Basal respiration and ( c ) maximal respiration measured following injection of uncoupler FCCP
Future large-scale randomized trials with extended follow-up and standardized respiratory endpoints are warranted to clarify durability and causal mechanisms
Several Phase 3 trials are expected to wrap up through 2026
Talk to your doctor if you have any worries about these side effects
The buffering of antioxidant species can be accomplished by reduced glutathione (GSH), that is also required for phase II detoxification in which endogenous and exogenous toxic metabolites are conjugated to GSH for their removal [10], [11]
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