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Biological analyses were performed on plasma samples, quantifying total and reduced glutathione, oxidized glutathione and redox ratios using HPLC with colorimetric detection, while behavioral outcomes were assessed weekly through standardized caregiver questionnaires and clinician-rated scales

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However, the expression level of ICAM-1 and VCAM-1 in total splenocytes and serum levels of chemotactic factors (i.e