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doi:10.1146/annurev.pharmtox.45.120403.095857

Though most of that work is focused on males, a few peptides have been shown to affect sperm parameters like motility and capacitation, highlighting that peptides can act on reproductive cells and their environment

Manufactured under strict quality control standards, Ipamorelin is suitable for: Peptide research and growth hormone secretagogue signaling studies Analytical laboratory investigations Biochemical analysis in controlled research models Product Details Specification: 10 mg vial CAS Number: 170851-70-4 Molecular Formula: CHNO Molecular Weight: 711.85 g/mol Purity: 99% (HPLC Tested) Designation: Research Use Only (RUO) This product is intended strictly for research purposes only and is not approved for human or veterinary use .

These are cell and tissue culture findings, not human clinical outcomes, so they don't directly translate to what a person using a topical serum would experience