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Gut distress is the most frequently reported mild side effect
It has been reported that there is no reduction in its secretion in patients with T2DM [13] but a nearly total loss of insulinotropic effect is observed, even at supraphysiological concentrations, implying the existence of GIP resistance [14]
The peptidoglycan recognition protein 1 confers immune evasive properties on pancreatic cancer stem cells
A second mechanism leading to hepatocellular hyperplasia is a consequence of shifts of existing hepatocyte populations from binucleated hepatocytes to mononucleated cells and shifts from a mononucleated tetraploid hepatocyte to two diploid hepatocytes (cytokinesis without nuclear duplication)
Exploring SGLT2 Inhibitors SGLT2 inhibitors, including empagliflozin (Jardiance), dapagliflozin (Farxiga), and canagliflozin (Invokana), offer a different therapeutic pathway
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