42 A phase 3 trial including adults with T2DM receiving orforglipron daily (3 mg, 12 mg or 36 mg) showed significant placebo-adjusted reductions in HbA 1c (1.07%) and weight loss (5.9%) at the highest dose
Semaglutide and tirzepatide can cause nausea, diarrhea, vomiting, constipation, abdominal (stomach) discomfort and pain, injection site reactions, fatigue, hypersensitivity (allergic) reactions (typically fever and rash), burping, hair loss and gastroesophageal reflux disease
Victoria's chief health officer on Friday issued a health alert, saying the department was aware of six cases of acute liver toxicity associated with the unapproved peptide product
Antibiotic-induced gut microbiota depletion enhances glucose tolerance linked to GLP-1 signaling
Some say yes