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Through interactions with PGC-1 coactivators and chromatin regulators, ERRs govern programs for mitochondrial biogenesis, oxidative phosphorylation (OXPHOS), lipid catabolism, and angiogenesis
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They mimic the action of endogenous glucagon-like peptide 1, a hormone involved in glucose regulation and appetite control
Derivano da e xendin-4 , un peptide isolato dalla saliva del Gila Monster ( heloderma suspectum ), una lucertola velenosa del sud dellArizona