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In a previous study, enhanced mTORC1 signaling was found to be dispensable for GC formation and serum antibody responses 102
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Avoid candies, especially those that you suck on and acidic foods
Meanwhile, hypoxia activates the HIF-1/PDK4 axis, which inhibits PDH activity and elevates mitochondrial membrane potential(MMP), suppressing the TCA cycle while enhancing glycolysis and lactate production, ultimately driving VSMC cell cycle progression and proliferation [86]
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