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Water retention: Temporary mild edema has been reported in IGF-1 interventions due to cell hydration effects

Chang JC, van der Hoeven LH, Haddox CH

Two-tailed tests were performed unless testing a direction hypothesis, in which case a one-tailed test was used

Both the thioredoxin (Trx) and GSH-dependent glutaredoxin (Grx) antioxidant systems have been found to reduce methionine sulfoxide reductases in vitro and/or in vivo (see Figure 2 ) (28)