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Stanley TL, Falutz J, Marsolais C, et al
However, oral delivery requires high doses due to gastric degradation and low intestinal bioavailability (typically less than 1%)
Popular GLP-1 receptor agonists, including GLP-1 injections for weight loss, have been extensively studied and clinically validated for their efficacy
Am J Physiol Gastrointest Liver Physiol (2019) 317(6):G824G38
Furthermore, bile acids (BAs) are intestinal microbial metabolites playing a major role in the MGBA
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