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In the Phase 2 trial protocol, participants began at a low starting dose commonly 2 mg once weekly before progressing through incremental increases over several months, with target maintenance doses ranging from 8 mg to 12 mg weekly depending on tolerability and clinical response

En un meta-anlisis realizado que incluy 13 ensayos clnicos con 3443 pacientes tratados con GLP1-RA y 2417 individuos en el grupo control se evidenci que la exenatida y liraglutida redujeron la presin arterial sistlica y diastlica entre 1 a 5 mmHg, comparado a otros frmacos como la insulina, glimepirida y el placebo 146

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