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In the brain, GLP-1 receptors act like a stop light and tell certain areas of the brain to stop releasing dopamine, the feel-good chemical that reinforces compulsive or addictive behavior, like alcohol consumption or over-eating, Varisco says

Eur J Heart Fail 19(1):6977 Lepore JJ, Olson E, Demopoulos L, Haws T, Fang Z, Barbour AM, Fossler M, Davila-Roman VG, Russell SD, Gropler RJ (2016) Effects of the novel long-acting GLP-1 agonist, albiglutide, on cardiac function, cardiac metabolism, and exercise capacity in patients with chronic heart failure and reduced ejection fraction

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Peptides Sublingual GHK-Cu vs Injectable GHK-Cu: Which Is More Effective

Besides some surprising new benefits, this approach can also discover rarer negative effects of the new drugs that might not be evident in clinical trials with much smaller sample sizes