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Cells were treated in triplicate with a serial dilution of IGF-1 LR3 for 4 hours

Notably, the disappearance of the slit diaphragm and the erasure of podocytic processes were observed ( Persistent proteinuria contributes to progressive renal impairment, ultimately leading to the destruction of physiological architecture, tubular atrophy, and interstitial fibrosis ( Table 1

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