2 Folate supplementation can correct these haematological effects of B12 deficiency but not the neurological complications, which include neuropathies, such as tingling and numbness in the arms and legs, sensory and motor disturbances, including abnormal gait, and cognitive changes
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Examples of drugs that are in the latter class include the anti-malarial drugs dapsone and primaquine, as well as rasburicase which is normally used in the treatment tumor lysis syndrome in patients undergoing chemotherapy for hematologic cancers, but has also been used to reduce the hyperuricemia associated with gout
provides metabolism support* Nervous System Support: Vitamin B12 (methylcobalamin) and folate (L-5-MTHF) support the nervous system, and function as hair, skin, and liver aids.* Cognitive Support: Folate is essential for fetal neural development