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Gastrointestinal side effects observed under cotadutide effects are similar in quality but more severe than those under GLP-1RA treatment ( Animal data on a GLP-1/GIP/glucagon triple agonist show strong effects on body weight reduction, and glucose- and lipid normalization in rodents

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When blood glucose levels rise after eating, these medications enhance insulin release while simultaneously suppressing glucagon secretion from alpha cells

Peptides are short sequences of amino acids, the building blocks of proteins