Obesity is still widely viewed as a personal responsibility problem, despite scientific evidence to the contrary
In addition to lowering blood sugar and promoting weight loss, GLP-1 medications have other potential health benefits, including lowering blood pressure and reducing heart disease risk
A recent comparison of GLP-1RAs versus placebo in both pediatric and adult populations demonstrated the significant efficacy of GLP-1RAs in promoting weight loss, highlighting their potential across diverse age groups (57)
More recently, tirzepatide a synthetic 39-amino-acid peptide that dual-agonizes GLP-1 and GIP receptors was approved as Mounjaro (diabetes, 2022) and Zepbound (obesity, 2023)
Siemieniuk RA, Meade MO, Alonso-Coello P, et al