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Patients are typically instructed to take the medication weekly at the same time while making lifestyle changes

Judge Robert Kirsch wrote that "clinical trials are complicated and nuanced, and investor calls are not scientific conferences." Get the market news that matters in a five-minute read with Market Briefs, our free daily newsletter Investors argue that Novo Nordisk's earlier communications glossed over this design feature, creating an expectation that nearly all participants would reach the highest dose and thus achieve maximum weight loss

Of note, almost half of patients treated with GLP-1-RAs also had pre-existing migraine as comorbidity (26.7% in the UCWM group), which could predispose them to worse (rather than better) headache outcomes [31], providing additional evidence of a favorable effect of GLP-1-RAs on headache improvement

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And weve talked offline a little bit about it, so itll be fun to dig in