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Graefes Arch Clin Exp Ophthalmol 262 , 717752 (2024)

Patients can resume regular activities immediately after treatment, although avoiding strenuous activity for a short period is advised

Aptamers-short, single-stranded oligonucleotides selected through systematic evolution of ligands by exponential enrichment (SELEX)-offer a powerful, flexible, and stable targeting modality ( We hypothesized that a fibrin-targeted, ROS-responsive GO nanocomposite encapsulating GSH (GO@GSH-FA) would selectively accumulate in ischemic brain regions and release its antioxidant payload in response to local oxidative stress