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139 The traditional techniques for evaluating the tumor immune microenvironment, including gene expression profiling, flow cytometry, and conventional immunohistochemistry, have limitations
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L-carnitine is a naturally occurring compound essential for transporting long-chain fatty acids into the mitochondria, where they are oxidised to produce energy
Ferroptosis is triggered in cells with dysregulated iron and thiol redox metabolism, whereby the initial robust but selective accumulation of hydroperoxy polyunsaturated fatty acid-containing phospholipids is further propagated through enzymatic and non-enzymatic secondary mechanisms, leading to formation of oxidatively truncated electrophilic species and their adducts with proteins
