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The GHK sequence also appears within the alpha-2(I) chain of type I collagen, leading to the hypothesis that collagen degradation at wound sites releases GHK fragments that then bind copper and signal for new collagen production, creating a self-repair feedback loop

However, N-acetylcysteine (NAC), a glutathione precursor, has the strongest clinical evidence and is used in NHS hospitals, making it a more reliable option despite not being a direct glutathione supplement

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Most patients have two to four sessions, four to six weeks apart, with the visible result developing over six to twelve weeks as the body clears the treated fat