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Glutathione attenuated gill apoptosis under hypoxia stress Caspases are pivotal regulators of apoptosis, with Caspase-8 and Caspase-9 belonging to the initiator caspases and Caspase-3 to the effector caspases [44]

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Besides, Pt-generated O 2 (Pongjit and Chanvorachote, 2011) and OH (Sumkhemthong et al., 2021) might also play pivotal roles in the development of PIPN

One unit of enzyme activity is the amount causing a change in absorbance of 0.001/min at 340 nm ( 2.18 Sorbitol dehydrogenase (SDH) and lactate dehydrogenase (LDH) The LDH assay is based on the inter-conversion of lactate and pyruvate and the SDH assay is based on inter-conversion of Fructose and Sorbitol