Study 4: Stier 2013, human safety analysis Citation: Stier H., Vos E., Kenley D
The effects of a lipid-based nutrient supplement and antiretroviral therapy in a randomized controlled trial on iron, copper, and zinc in milk from HIV-infected Malawian mothers and associations with maternal and infant biomarkers
TB-500 is frequently dosed in larger loading amounts up front and lower maintenance amounts later, so saving the setup avoids re-deriving the units each phase
It can also reduce DHEA, which supports androgen production
Over the decades, the EAE model, focused primarily on T cells, has been the model for MS pathogenesis and treatment studies (Preiningerova et al., 2022)