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For newer medicines such as semaglutide and tirzepatide, regain averaged 0.8 kg (~1.8 pounds) per month, with projections indicating return to baseline by approximately 1.5 years - though information on weight change beyond 12 months after these drugs remains limited

Induration indicates a more significant inflammatory response than simple erythema, with cellular infiltration creating a palpable mass

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A clear understanding of how semaglutide and tirzepatide work, along with their different side effects, helps patients set achievable targets and maintain treatment adherence

This dual agonism enhances insulin secretion in a glucose-dependent manner, meaning insulin is released only when blood glucose levels are elevated, thereby reducing the risk of hypoglycaemia