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PMID: 27977392

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Methods In this study, we investigated the add-on potential of the dual amylin and calcitonin receptor agonist (DACRA) KBP-089 in combination with the GLP-1 receptor agonist liraglutide as obesity treatment in high-fat diet (HFD) fed rats

Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations AML: acute myeloid leukemia AP-1: activator protein-1 ASK1: apoptosis signal-regulating kinase 1 BCNU: N,N -bis(2-chloroethyl)- N -nitrosourea CDNB: 1-chloro-2,4-dinitrobenzene CFU-GM: colony forming unit-granulocyte, monocyte DXR: doxorubicin EA: ethacrynic acid ERK: extracellular signal-regulated kinase 5-FU: 5-fluorouracil GSH: glutathione GST: glutathione S -transferase H 2 O 2 : hydrogen peroxide HEL: Haloenol lactone HFF: human foreskin fibroblast JNK: c-Jun N-terminal kinase MAPK: mitogen-activated protein kinase MAPEG: membrane-associated proteins in eicosanoid and glutathione MDS: myelodysplastic syndrome NCI: National Cancer Institute NTZ: nitazoxanide ROS: reactive oxygen species TLK117: ( -glutamyl- S -(benzyl)cysteinyl- R (-)-phenylglycine) TRAF2: TNF receptor-associated factor 2 UV: ultraviolet References Litwack G, Ketterer B, Arias IM

A small 2021 study found that people living with obesity reduced their body fat using the supplement for 12 weeks, but only 60 individuals were involved in the study, and it did not involve a patch