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In the other direction, the brain may exert an influence on the gut, either via the autonomic and enteric nervous systems (downwards black arrows in Figure 2 ), or via activation of the Hypothalamus-Pituitary-Adrenal (HPA) axis (downwards red arrows in Figure 2 ), which will be examined in detail later

doi: 10.1016/j.redox.2020.101562 124 OckC-Y

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In many cases, your provider will require something called a prior authorizationa formal approval process that confirms the medication is medically necessary for your specific situation

The neonatal-onset form of the disease is the more common form of propionic acidemia