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Furthermore, we propose that the manipulation of gut microbiota represents a clinical therapeutic potential for lessening the development and consequence of appetite-related disorders

The light intensity for the testing environment of OFT (center 10 lux, peripheral 6 lux), EPM (open arm 35 lux, close arm 20 lux), Novel cage locomotion test (15 lux), wire hanging test (600 lux), ledge test (600 lux), hindlimb clasping test (600 lux), novel object recognition test (15 lux)

Pyroptosis A form of programmed cell death triggered by infection or cellular stress that is, unlike apoptosis, characterized by inflammation as it involves the activation of inflammasomes and caspase-1, leading to cell swelling, membrane rupture and the release of pro-inflammatory cytokines such as interleukin-1 (IL-1) and IL-18

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The number of treatments required differs from person to person, depending on the area being treated and personal objectives